TRACK-TBI NET is a multi-faceted Phase 2 traumatic brain injury (TBI) clinical trial network built upon the established infrastructure of the longitudinal, observational TRACK-TBI study. This institutional and public–private partnership includes 18 Clinical Enrollment and Study Sites, 7 specialized Cores, and an Academic Contract Research Organization, encompassing nearly 50 collaborating institutions, industry partners, and philanthropic organizations.
Following more than a decade of foundational work, the TRACK-TBI Network is now positioned to transition from an observational natural history study into a scalable platform for interventional TBI trials. Supported in part by the U.S. Department of Defense through the Defense Health Agency Operational Medical Systems (DHA OPMED), Warfighter Readiness, Performance, and Brain Health Project Management Office (Fort Detrick, MD), and administered via the Medical Technology Enterprise Consortium, the Network has initiated an adaptive Phase 2 platform clinical trial designed to accelerate therapeutic development in TBI.