Performance of the IMPACT and CRASH prognostic models for traumatic brain injury in a contemporary multicenter cohort: A TRACK-TBI Study.

Yue JK, Lee YM, Sun X, van Essen TA, Elguindy MM, Belton PJ, Pisică D, Mikolic A, Deng H, Kanter JH, McCrea MA, Bodien YG, Satris GG, Wong JC, Ambati VS, Grandhi R, Puccio AM, Mukherjee P, Valadka AB, Tarapore PE, Huang MC, DiGiorgio AM, Markowitz AJ, Yuh EL, Okonkwo DO, Steyerberg EW, Lingsma HF, Menon DK, Maas AIR, Jain S, Manley GT; The TRACK-TBI Investigators. J Neurosurg. 2024 Mar 15:1-13. PMID 38489823. <<PubMed>>


Isolated Traumatic Subarachnoid Hemorrhage on Head Computed Tomography Scan May Not Be Isolated: A TRACK-TBI Study.

Yue JK, Yuh EL, Elguindy MM, Sun X, Van Essen TA, Deng H, Belton PJ, Satris GG, Wong JC, Valadka A, Korley FK, Robertson CS, McCrea M, Stein MB, Diaz-Arrastia R, Wang KKW, Temkin N, DiGiorgio AM, Tarapore PE, Huang MC, Markowitz A, Puccio AM, Mukherjee P, Okonkwo DO, Jain S, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2024 Mar 7. PMID 38450561. <<PubMed>>


Association of Biomarkers of Neuronal Injury and Inflammation With Insomnia Trajectories After Traumatic Brain Injury: A TRACK-TBI Study.

Werner JK, Albrecht J, Capaldi VF, Jain S, Sun X, Mukherjee P, Williams SG, Collen J, Diaz-Arrastia R, Manley GT, Krystal AD, Wickwire E; TRACK-TBI Investigators. Neurology. 2024 Apr 23;102(8):e209269. PMID 38547447. <<PubMed>>


MaPPeRTrac: A Massively Parallel, Portable, and Reproducible Tractography Pipeline.

Cai LT, Moon J, Camacho PB, Anderson AT, Chwa WJ, Sutton BP, Markowitz AJ, Palacios EM, Rodriguez A, Manley GT, Shankar S, Bremer PT, Mukherjee P, Madduri RK; TRACK-TBI Investigators. Neuroinformatics. 2024 Mar 6. PMID 38446357. <<PubMed>>


Diagnostic Utility of Glial Fibrillary Acidic Protein Beyond 12 Hours After Traumatic Brain Injury: A TRACK-TBI Study.

Puccio AM, Yue JK, Korley FK, Okonkwo DO, Diaz-Arrastia R, Yuh EL, Ferguson AR, Mukherjee P, Wang KKW, Taylor SR, Deng H, Markowitz AJ, Sun X, Jain S, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2024 Mar 14. PMID 38251868. <<PubMed>>


Profiles of Cognitive Functioning at 6 Months After Traumatic Brain Injury Among Patients in Level I Trauma Centers: A TRACK-TBI Study.

Bryant AM, Rose NB, Temkin NR, Barber JK, Manley GT, McCrea MA, Nelson LD; TRACK-TBI Investigators. JAMA Netw Open. 2023 Dec 1;6(12):e2349118. PMID 38147333. <<PubMed>>


Association of Early Dexmedetomidine Utilization With Clinical and Functional Outcomes Following Moderate-Severe Traumatic Brain Injury: A Transforming Clinical Research and Knowledge in Traumatic Brain Injury Study 

Liu SY, Kelly-Hedrick M, Temkin N, Barber J, Komisarow J, Hatfield J, Ohnuma T, Manley GT, Treggiari, MM, Colton K, Vavilala M, Grandhi, R, Laskowitz D, Mathew JP, Hernandez A, James ML, Raghunathan K, Goldstein B, Markowitz A, Krishnamoorthy V and  The Transforming Clinical Research and Knowledge in TBI (TRACK-TBI) Investigators. <<PubMed>>


Recovery potential in patients who died after withdrawal of life-sustaining treatment: A TRACK-TBI propensity score analysis

Liu SY, Kelly-Hedrick M, Temkin N, Barber J, Komisarow J, Hatfield J, Ohnuma T, Manley GT, Treggiari, MM, Colton K, Vavilala M, Grandhi, R, Laskowitz D, Mathew JP, Hernandez A, James ML, Raghunathan K, Goldstein B, Markowitz A, Krishnamoorthy V and  The Transforming Clinical Research and Knowledge in TBI (TRACK-TBI) Investigators. <<PubMed>>


Clinical Outcomes After Traumatic Brain Injury and Exposure to Extracranial Surgery: A TRACK-TBI Study

Roberts CJ, Barber J, Temkin NR, Dong A, Robertson CS, Valadka A, Yue JK, Markowitz AJ, Manley GT, Nelson LD, and Transforming Clinical Research and Knowledge in TBI (TRACK-TBI) Investigators. JAMA Surg. 2023 Dec 13. <<PubMed>>


Data-driven distillation and precision prognosis in traumatic brain injury with interpretable machine learning.

Tritt A, Yue JK, Ferguson AR, Torres Espin A, Nelson LD, Yuh EL, Markowitz AJ, Manley GT, Bouchard KE; TRACK-TBI Investigators. Sci Rep. 2023 Dec 1;13(1):21200. PMID 38040784. <<PubMed>>


Network analysis and relationship of symptom factors to functional outcomes and quality of life following mild traumatic brain injury: a TRACK-TBI study

Eagle SR , Jain S, Sun X, Preszler J, McCrea MA, Giacino JT, Manley GT, Okonkwo DO, Nelson LD and the TRACK-TBI Investigators. Front Neurol. 12 DEC 2023. <<PubMed>>


Profiles of Cognitive Functioning at 6 Months After Traumatic Brain Injury Among Patients in Level I Trauma Centers

Bryant AM, Rose N, Temkin NR, Barber JK, Manley GT, McCrea MA, Nelson LD, and the TRACK-TBI Investigators. JAMA Network Open. 26 Dec 2023. <<PubMed>>


Predicting Functional Dependency in Patients with Disorders of Consciousness: A TBI-Model Systems and TRACK-TBI Study

Snider SB, Temkin NR, Barber J, Edlow BL, Giacino JT, Hammond FM, Izzy S, Kowalski RG, Markowitz AJ, Rovito CA, Shih SL, Zafonte RD, Manley GT, Bodien YG; TRACK-TBI investigators. Annals of Neurology. 23 July 2022. <<PubMed>>


Longitudinal Recovery Following Repetitive Traumatic Brain Injury.

Etemad LL, Yue JK , Barber J, Nelson LD, Bodien Y, Satris GG, Belton PJ, Madhok DY, Huie JR, Hamidi S, Tracey J, Coskun B, Wong JC, Yuh EL, Mukherjee P, Markowitz AJ, Huang M, Tarapore PE, Robertson C, Diaz-Arrastia R, Stein MB, Ferguson AR, Puccio AM, Okonkwo DO, Giacino J, McCrea M, Manley GT, Temkin N, DiGiorgio AM, and the TRACK-TBI Investigators. JAMA Network Open. <<PubMed>>


Prevalence of and Risk Factors for Post-traumatic Headache in Civilian Patients After Mild Traumatic Brain Injury: A TRACK-TBI Study.

Ashina H, Dodick DW, Barber J, Temkin NR, Chong CD, Adler JS, Stein KS, Schwedt TJ, Manley GT; TRACK-TBI Investigators. Mayo Clin Proc. 2023 Oct;98(10):1515-1526. PMID 37480909. <<PubMed>>


Long-term Multi-domain Patterns of Change Following Traumatic Brain Injury: A TRACK-TBI LONG Study 

Brett BL, Temkin N, Barber J, Okonkwo DO, Stein M, Bodien YB, Corrigan J, Diaz-Arrastia R, Giacino JT, McCrea MA, Manley GT, and Nelson LD for the TRACK-TBI Investigators. Neurology. 2023 Jun 21. <<PubMed>>


Association of Obesity with Mild Traumatic Brain Injury Symptoms, Inflammatory Profile, Quality of Life, and Functional Outcomes: a TRACK-TBI Study

Eagle SR, Puccio AM, Nelson LD, McCrea MA, Giacino JT, Diaz-Arrastia R, Conkright W, Jain SO, Sun X, Manley GT, and Okonkwo DO. Journal of Neurology, Neurosurgery, and Psychiatry. 2023 Jun 27. <<PubMed>>


Effects of age and time since injury on traumatic brain injury blood biomarkers: a TRACK-TBI study 

Gardner RC, Puccio AM, Korley FK, Wang KW, Diaz-Arrastia R, Okonkwo DO, Puffer RC, Yuh EL, Yue JK, Sun X, Taylor SR, Mukherjee P, Jain SO, Manley GT, and the TRACK-TBI Investigators. Brain Communications. eCollection 2023.<<PubMed>>


Neuroworsening in the Emergency Department is a Predictor of Traumatic Brain Injury Intervention and Outcome: A TRACK-TBI Pilot Study.

Yue JK, Krishnan N, Kanter JH, Deng H, Okonkwo DO, Puccio AM, Madhok DY, Belton PJ, Lindquist BE, Satris GG, Lee YM, Umbach G, Duhaime AC, Mukherjee P, Yuh EL, Valadka AB, DiGiorgio AM, Tarapore PE, Huang MC, Manley GT; TRACK-TBI Investigators. J Clin Med. 2023; 12(5):2024. <<PubMed>>


Associations of Microvascular Injury-Related Biomarkers with Traumatic Brain Injury Severity and Outcomes: A TRACK-TBI Pilot Study.

Schneider ALC, Huie JR, Jain S, Sun X, Ferguson AR, Lynch C, Yue JK, Manley GT, Wang KWW, Sandsmark DK, Campbell C, Diaz-Arrastia R, and the TRACK-TBI Study Investigators. Journal of Neurotrauma. 2023 May 18, <<PubMed>>


Neuroinflammatory Biomarkers for Traumatic Brain Injury Diagnosis and Prognosis: A TRACK-TBI Pilot Study

Yue JK, Kobeissy FH, Jain S, Sun X, Phelps RRL, Korley FK, Gardner RC, Ferguson AR, Huie JR, Schneider ALC, Yang Z, Xu H, van Essen TA, Satris GG, Lynch CE, Deng H, Madhok DY, Rabinowitz M, Vassar MJ, Taylor SR, Mukherjee P, Yuh EL, Markowitz AJ, Puccio AM, Okonkwo DO, Diaz-Arrastia R, Manley GT, Wang KKW and the TRACK-TBI Investigators. Neurotrauma Reports. 2023 Mar 24;4(1):171-183. <<PubMed>>


Functional recovery, symptoms, and quality of life 1–5 years after traumatic brain injury: A TRACK-TBI study

Nelson LD, Temkin NR, Barber J, Brett BL, Okonkwo DO, McCrea MA, Giacino JT, Bodien YG, Robertson C, Corrigan JD, Diaz-Arrastia R, Markowitz JD, Manley GT & the TRACK-TBI Investigators. JAMA Netw Open. 2023;6(3):e233660. doi:10.1001/jamanetworkopen.2023.3660.


Polygenic risk for mental disorders as predictors of posttraumatic stress disorder after mild traumatic brain injury

Stein MB, Jain S, Parodi L, Choi KW, Maihofer AX, Nelson LD, Mukherjee P, Sun X, He F, Okonkwo DO,  Giacino JT, Korley FK, Vassar M, Robertson CS, McCrea MA, Temkin N, Markowitz AJ, Diaz-Arrastia R, Rosand J, Manley GT, and the TRACK-TBI Investigators. Transl Psychiatry. 2023 Jan 25;13(1):24. <<PubMed>>


Feasibility and utility of a flexible outcome assessment battery for longitudinal traumatic brain injury research: A TRACK-TBI study

Bodien YG, Barber J, Taylor SR, Boase KD, Corrigan JD, Dikmen S, Gardner RC, Kramer J, Levin H, Machamer J, McAllister T, Nelson LD, Ngwenya LB, Sherer M, Stein MB, Vassar MJ, Whyte J, Yue JK, Markowitz AJ, McCrea M, Manley GT, Temkin N, Giacino J. J Neurotrauma. 2022 Sep 13. Epub ahead of print. <<PubMed>>


Longitudinal White Matter Microstructural Correlates of Emotional Resilience versus Neuropsychiatric Distress following Mild Traumatic Brain Injury

Cai LT, Brett BL, Palacios EM, Yuh EL, Bourla I, Wren-Jarvis J, Wang Y, Mac Donald CL, Vassar MJ, Diaz-Arrastia R, Giacino JT, Okonkwo DO, Robertson CS, Stein MB, Temkin N, McCrea MA, Markowitz AJ, Manley GT, McCrea MA, Zafonte RD, Nelson LD, Mukherjee P; TRACK-TBI Investigators. Biol Psychiatr Cogn Neurosci Neuroimaging. 2022 Sep 21:S2451-9022(22)00231-2.


Outcomes in Patients With Mild Traumatic Brain Injury Without Acute Intracranial Traumatic Injury

Madhok DY, Rodriguez RM, Barber J, Temkin NR, Markowitz AJ, Kreitzer N, Manley GT, and the TRACK-TBI Investigators.  JAMA Netw Open. 2022 Aug 1;5(8).  <<PubMed>>  


Diffusion Tensor Imaging Reveals Elevated Diffusivity of White Matter Microstructure that Is Independently Associated with Long-Term Outcome after Mild Traumatic Brain Injury: A TRACK-TBI Study

Palacios EM, Yuh EL, Mac Donald CL, Vassar MJ, Diaz-Arrastia R, Giacino JT, Okonkwo DO, Robertson CS, Stein MB, Temkin N, McCrea MA, Levin HS, Markowitz AJ, Jain S, Manley GT, Mukherjee P; TRACK-TBI Investigators.  J Neurotrauma. 2022 Jul 18. doi: 10.1089/neu.2021.0408. Online ahead of print. <<PubMed>>


Prognostic Value of Day-of-Injury Plasma GFAP and UCH-L1 levels for Predicting Functional Recovery in the TRACK-TBI Cohort: an Observational Cohort Study

Korley F, Jain S, Sun X, Puccio A, Yue JK, Gardner RC, Wang KKW, Okonkwo DO, Yuh E, Mukherjee P, Nelson L, Taylor SR, Markowitz AJ, Diaz-Arrastia R, Manley GT and the TRACK-TBI Investigators. The Lancet Neurology2022 Sep;21(9):803-813. <<PubMed>>   


Employment and Economic Outcomes of Mild Traumatic Brain Injury Participants in the TRACK-TBI Study        

Gaudette E, Seabury S, Temkin N, Barber J, DiGiorgio A, Markowitz AJ, Manley GT and the TRACK-TBI Investigators. JAMA Network Open. 2022 June 1. <<PubMed>>


Association of Day-of-Injury Serum Glial Fibrillary Acidic Protein Concentration and Six-Month Posttraumatic Stress Disorder in Patients with Mild Traumatic Brain Injury

Kulbe JR, Jain S, Nelson LD, Korley FK, Mukherjee P,  Sun X, Okonkwo DO, Giacino JT, Vassar M, Robertson C, McCrea MA, Wang KKW, Temkin N,  Mac Donald C,  Taylor S, Ferguson AR, Markowitz AJ, Diaz-Arrastia R, Manley GT, Stein MB, and the TRACK-TBI Investigators. Neuropsychopharmacology. 2022 June 18. <<PubMed>>


The Case for Optimized Edge-Centric Tractography at Scale

Moon J, Mukherjee P, Madduri R, Markowitz AJ, Palacios EM, and Manley GT. Frontiers in Neuroinformatics. 16 May 2022. <<PubMed>>


Incidence and Clinical Impact of Myocardial Injury Following Traumatic Brain Injury: A Pilot TRACK-TBI Study

Krishnamoorthy V, Manley GT, Jain S, Sun S, Foreman B, Komisarow, Laskowitz DT, Mathew JP, Hernandez A, James ML, Vavilala MS, MD, Markowitz AJ, Korley FK,  and the TRACK-TBI Investigators. J Neurosurg Anesthesiol. 2022 Apr 1;34(2):233-237. <<PubMed>>


Trajectories of insomnia in adults after traumatic brain injury

Wickwire EM, Albrecht JS, Capaldi VF, Jain SO, Gardner RC, Werner JK, Mukherjee P, McKeon AB, Smith MT, Giacino JT, Nelson LD, Williams SG, Collen J, Sun X, Schnyer DM, Markowitz AM, Manley GT, & Krystal AD. JAMA Network Open. 2022 Jan 4;5(1):e2145310 <<PubMed>>


Effect of frailty on 6-month outcome after traumatic brain injury: a multicentre cohort study with external validation

Galimberti S, Graziano F, Maas A, Isernia G, Lecky F, Jain S, Sun X, Gardner R, Taylor SR, Markowitz AJ, Manley GT, Valsecchi G, Bellelli G, Citerio G and CENTER-TBI & TRACK-TBI Investigators. The Lancet Neurology. 2022 Feb;21(2):153-162. <<PubMed>>


Mixture Model Framework for Traumatic Brain Injury Prognosis Using Heterogeneous Clinical and Outcome Data.

Kaplan AD, Cheng Q, Mohan KA, Nelson LD, Jain S, Levin H, Torres-Espin A, Chou A, Huie JR, Ferguson AR, Mccrea M, Giacino J, Sundaram S, Markowitz AJ, Manley GT. IEEE J Biomed Health Inform. 2022 Mar;26(3):1285-1296. <<PubMed>>


Comparing the Quality of Life after Brain Injury-Overall Scale and Satisfaction with Life Scale as Outcome Measures for Traumatic Brain Injury Research

Kreitzer N, Jain S , Young JS, Sun X, Stein MB, McCrea M, Levin HS, Giacino J, Markowitz AJ, Manley GT, Nelson LD,  and the TRACK-TBI Investigators. J Neurotrauma. 2021 Dec;38(23):3352-3363.  <<PubMed>>


Blood-based traumatic brain injury biomarkers - Clinical utilities and regulatory pathways in the United States Europe and Canada

Wang KK, Munoz Pareja  JC, 3, Mondello S, Diaz-Arrastia R,  5 , Wellington C,  6, Kenney K, Puccio AM,  Hutchison J,  McKinnon N,  Okonkwo DO,  Yang Z, Kobeissy F, Tyndall JA, Büki A, Czeite E , Pareja Zabala MC, Gandham N, Berman R, and the InTBIR Biospecimens/Biomarkers Working Group. Expert Rev Mol Diagn. 2021 Dec;21(12):1303-1321. <<PubMed>>


Relationship Between Transdiagnostic Dimensions of Psychopathology and Traumatic Brain Injury (TBI): A TRACK-TBI Study

Nelson LD, Kramer MD, Joyner KJ, Patrick CJ, Stein MB, Temkin N, Levin HS, Whyte J, Markowitz AJ, Giacino JT, Manley GT and the TRACK-TBI Investigators. J Abnorm Psychol. 2021 Jul;130(5):423-434. <<PubMed>>


Diagnosing Level of Consciousness: The Limits of the Glasgow Coma Scale Total Score

Bodien YG, Barra A, Temkin NR, Barber J, Foreman B, Vasser M, Robertson C, Taylor SR, Markowitz AJ, Manley GT, Giacino JT, Edlow BL, and the TRACK-TBI Investigators. J Neurotrauma. 2021 Dec;38(23):3295-3305. <<PubMed>>


Association of Posttraumatic Epilepsy With 1-Year Outcomes After Traumatic Brain Injury

Burke J, Gugger J, Ding K, Kim JA, Foreman B, Yue JK, Puccio AM, Yuh EL, MD, Sun X, Rabinowitz M, Vassar M, Taylor SR, Winkler EA, MD, Deng H, McCrea M, Stein MB, MD, Robertson CS, Levin HS, Dikmen S, Temkin NR, Barber J, Giacino JT, Mukherjee P, Wang KK, Okonkwo DO, Markowitz AJ, Jain SJ, Lowenstein D, Manley GT, Diaz-Arrastia, and the TRACK-TBI Investigators. JAMA Netw Open. 2021;4(12):e2140191. doi:10.1001/jamanetworkopen.2021.40191 <<Link>>


Prognostic Value of Hemorrhagic Brainstem Injury on Early Computed Tomography: A TRACK-TBI Study

Williams  JR, Nieblas-Bedolla E, Feroze A, Young C , Temkin NR, Giacino JT, Okonkwo DO, Manley GT, Barber J, Durfy  S, Markowitz AJ, Yuh EL, Mukherjee P, Mac Donald CL, and TRACK-TBI Investigators. Neurocrit Care. 2021 Dec;35(3):927. <<PubMed>>


Association of Vasopressor Choice with Clinical and Functional Outcomes Following Moderate to Severe Traumatic Brain Injury: A TRACK-TBI Study.

Toro C, Temkin N, Barber J, Manley G, Jain S, Ohnuma T, Komisarow J, Foreman B, Korley FK, Vavilala MS, Laskowitz DT, Mathew JP, Hernandez A, Sampson J, James ML, Goldstein BA, Markowitz AJ, Krishnamoorthy V and the TRACK-TBI Investigators. Neurocrit Care. 2021 Aug 2. Online ahead of print. <<PubMed>>


Characterization and standardization of multiassay platforms for four commonly studied traumatic brain injury protein biomarkers: a TBI Endpoints Development Study

Sarkis G, Zhu T,  Yang Z,  Li X, Shi Y, Rubenstein R, Yost RA, Manley GT, Wang KK. Biomark Med.  2021 Dec;15(18):1721-1732. Epub 2021 Oct 22. <<PubMed>>


Pathological Computed Tomography Features Associated with Incomplete Recovery and Unfavorable Outcome After Mild Traumatic Brain Injury: A TRACK-TBI Study

Yuh EL, Jain S, Sun X, Pisica D, Harris M, Taylor SR, Markowitz AJ, Mukherjee P, Verheyden J, Giacino JT, Levin HS, McCrea M, Stein MB, Temkin NR, Diaz-Arrastia R, Robertson CS, Lingsma, Okonkwo DO, Maas A, Manley GT and The TRACK-TBI  and CENTER-TBI Investigators. JAMA Neuroldoi:10.1001/jamaneurol.2021.2120. 19 July 2021. Online ahead of print.


Functional Outcome Over the First Year after Moderate-to-Severe Traumatic Brain Injury: A Prospective, Longitudinal TRACK-TBI Study

McCrea MA,  Giacino JT, Barber J. Temkin NR, Nelson LD, Levin HS, Dikmen S, Stein M, Bodien YG, Boase K, Taylor SR, Vassar M, Mukherjee P, Robertson CS, Diaz-Arrastia R, Okonkwo DO, Markowitz AJ, Manley GT and the TRACK-TBI Investigators. JAMA Neurol. 2021 Jul 6. doi: 10.1001/jamaneurol.2021.2043. Online ahead of print.


Latent Profile Analysis of Neuropsychiatric Symptoms and Cognitive Function of Adults 2 Weeks After Traumatic Brain Injury Findings From the TRACK-TBI Study

Brett BL, Kramer MD, Whyte J, McCrea MA, Stein MB, Giacino JT, Sherer M, Markowitz AJ, Manley GT, Nelson, LD Ph; and the TRACK-TBI Investigators. JAMA Netw Open. 2021;4(3):e213467.


Central curation of Glasgow Outcome Scale- Extended (GOSE) data: lessons learned from TRACK-TBI

Boase K, Machamer J, Temkin NR, Dikmen S, Wilson L, Nelson LD, Barber J, Bodien YG, Giacino JT, Markowitz AJ, McCrea M, Satris G, Stein MB, Taylor SR, Manley GT. J Neurotrauma. 2021 Sep 1;38(17):2419-2434. <<PubMed>>


A Manual for the Glasgow Outcome Scale-Extended (GOSE) Interview.

Wilson L, Boase K, Nelson LD, Temkin NR, Giacino JT, Markowitz AJ, Maas A, Menon DK,  Teasdale G, Manley GT. J Neurotrauma. 2021 Sep 1;38(17):2435-2446. <<PubMed>>


Discrepancies in national databases for TBI estimates

Madhok DY, Hsia RY, Manley GT. Journal of Neurosurgery Letter to the Editor. Published online March 19, 2021; DOI: 10.3171/2020.12.JNS204327.


Relationship between transdiagnostic dimensions of psychopathology and traumatic brain injury (TBI): A TRACK-TBI study

Nelson LD, Kramer MD, Joyner KJ, Patrick CJ, Stein MB, Temkin N, Levin HS, Whyte J, Markowitz AJ, Giacino J, Manley GT and  the TRACK-TBI Investigators. Journal of Abnormal Psychology. Advance online publication. doi: 10.1037/abn0000672


Smaller regional brain volumes predict posttraumatic stress disorder at 3 months after mild traumatic brain injury

Stein MB, Yuh E, Jain S, Okonkwo DO, MacDonald CL, Levin H, Giacino JT, Robertson CS, Nelson LD, McCrea MA, Sun X, Temkin N, Taylor SR, Markowitz AJ, Manley GT, Mukherjee P and the TRACK-TBI Investigators. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 6, 352-359. doi: 10.1016/j.bpsc.2020.10.008


A Comparison of GFAP and UCH-L1 Measurements from Two Prototype Assays: The Abbott i-STAT™ Alinity™ and ARCHITECT® Assays

Korley F, Datwyler SA, Jain S, Sun X, Beligere G, Chandran R, Marino J, McQuiston B, Zhang H, Caudle KL, Wang K, Puccio AM, Okonkwo DO, Yue JK, Taylor SR, Manley GT, Diaz-Arrastia R. In Press. Neurotrauma Reports. February 2021


Association of Gender and Age with Mild Traumatic Brain Injury-Related Symptoms: A TRACK-TBI Study

Levin HS, Temkin NR, Barber J Nelson LD, Robertson C, Brennan J, Stein MB, Yue JK, Giacino JT, McCrea M, Diaz-Arrastia R, Mukherjee P, Okonkwo DO, Boase K, Markowitz AJ, Bodien Y, Taylor SR, Vassar MJ, Manley GT  and the TRACK-TBI Investigators. JAMA Netw Open. 2021;4(4):e213046. doi:10.1001/jamanetworkopen.2021.3046


High-sensitivity C-Reactive Protein is a Prognostic Biomarker of 6-month Disability After Traumatic Brain Injury: Results from the TRACK-TBI Study

Xu L,  Yue JK, Korley FK, Puccio  AM, Yuh EL, Sun X, Rabinowitz  M, Vassar M, Taylor SR, Ethan A Winkler EA, Puffer R, Deng H, McCrea M, Stein MB, Robertson CS, Levin H, Dikmen S, Temkin N, Giacino JT, Mukherjee P, Wang KW, Okonkwo DO, Markowitz AJ, Jain S, Manley GT, Diaz-Arrastia R. J Neurotrauma. 2020 Nov 9. Online ahead of print. <<PubMed>>


Validity of the Brief Test of Adult Cognition by Telephone (BTACT) in Level 1 Trauma Center Patients 6 Months Post-Traumatic Brain Injury: A TRACK-TBI Study  

Nelson LD, Barber J, Temkin N, Dams-O’Connor K, Dikmen S, Giacino JT, Kramer M, Levin HS, McCrea M, Whyte J, Bodien YG, Yue JK, Manley GT and the TRACK-TBI Investigators. J Neurotrauma. 2020 Oct 27. Online ahead of print. <<PubMed>>


Point-of-Care Platform Blood Biomarker Testing of GFAP versus S100B for Prediction of Traumatic Brain Injuries: a TRACK-TBI study

Okonkwo DO, Puffer RC,  Puccio AM, Yuh EL, Yue JK, Diaz-Arrastia R, Korley FK, Wang KW, Sun X, Taylor SR,  Mukherjee P, Markowitz AJ, Jain S, Manley GT and the TRACK-TBI Investigators. J Neurotrauma. 2020 Sep 14. Online ahead of print. <<PubMed>>


Risk Factors for Suicidal Ideation Following Mild Traumatic Brain Injury: A TRACK-TBI Study

Campbell-Sills L, Jain S, Sun X, Fisher LB, Agtarap SD, Dikmen S, Nelson LD, Temkin N, McCrea M, Yuh E, Giacino JT, Manley GT, Stein MB; TRACK-TBI Investigators. J Head Trauma Rehabil. 2020 Jul 22. Online ahead of print. <<PubMed>>


Polytrauma Is Associated with Increased Three- and Six-Month Disability after Traumatic Brain Injury: A TRACK-TBI Pilot Study

Yue JK, Satris GG, Dalle Ore CL, Huie JR, Deng H, Winkler EA, Lee YM, Vassar MJ, Taylor S, Schnyer DM, Lingsma HF, Puccio AM, Yuh EL, Mukherjee P, Valadka AB, Ferguson AR, Markowitz AJ, Okonkwo DO, Manley GT and the TRACK-TBI Investigators. Neurotrauma Reports. Vol. 1, No. 1. July 2020.


Satisfaction with Life Following Mild Traumatic Brain Injury: A TRACK-TBI Study

Agtarap, SD, Campbell-Sills, L, Jain, S, Sun, X, Dikmen, S, Levin, H, McCrea, MA, Mukherjee, P, Nelson, LD, Temkin, N, Yuh, E, Giacino, JT, Manley, GT, Stein, MB & the TRACK-TBI Investigators. J Neurotrauma. 2020 Dec 14. <<PubMed>>


The evolution of white matter changes after mild traumatic brain injury: A DTI and NODDI study.

Palacios EM, Owen J, Yuh EL, Wang M, Vassar MJ, Ferguson AR, Diaz-Arrastia R, Giacino J, Okonkwo DO, Robertson CS, Stein MB, Temkin NR, Jain S, McCrea M, Mac Donald C, Levin HS, Manley GT, Mukherjee P. Sci Adv. 2020 Aug 7;6(32) 2020 Aug. <<PMID>>


Assessing physical function and mobility following pediatric traumatic brain injury with the NIH Toolbox Motor Battery: A feasibility study.

Evans E,  Cook NE,  Iverson G, Townsend EL, Duhaime, AC, and TRACK-TBI Investigators.  Phys Occup Ther Pediatr. 2020 May 12;1-18. <<PubMed>>


Clinical Predictors of 3- and 6-Month Outcome for Mild Traumatic Brain Injury Patients with a Negative Head CT Scan in the Emergency Department: A TRACK-TBI Pilot Study.

Madhok DY, Yue JK, Sun X, Suen, Coss N, Jain S, Manley GT,  and the TRACK-TBI Investigators. Brian Sciences. 1 May 2020. <<PubMed>>


Monitoring outcome after hosptial-presenting milder spectrum pediatric traumatic brain injury using the Glasgow Outcome Scale Extended, Pediatric Revision.

Evans E,  Cook NE,  Iverson G, Townsend EL, Duhaime, AC, and TRACK-TBI Investigators. Monitoring.  J Neurotrauma. April 2020. Epub ahead of print. <<PubMed>>


Substance use on admission toxicology screen is associated with peri-injury factors and six-month outcome after traumatic brain injury: A TRACK-TBI Pilot study.

Yue JK, Phelps RRL, Winkler EA, Deng H, Upadhyayula PS, Vassar MJ, Madhok DY, Schnyer DM, Puccio AM, Lingsma HF, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT; TRACK-TBI Investigators. J Clin Neurosci2020 Mar 12. Epub ahead of print. PMID 32173156. <<PubMed>>


Biomarkers for traumatic brain injury: Data standards and statistical considerations.

Huie JR, Mondello S, Lindsell C, Antiga L, Yuh EL, Zanier ER, Masson S, Rosario B, Ferguson AR; TRACK-TBI Investigators. J Neurotrauma2020 Feb 11. Epub ahead of print. PMID 32046588. <<PubMed>>


Statistical guidelines for handling missing data in traumatic brain injury clinical research.

Nielson JL, Cooper SR, Seabury SA, Luciani D, Fabio A, Temkin NR, Ferguson AR; TRACK-TBI Investigators. J Neurotrauma2020 Mar 10. Epub ahead of print. PMID 32008424 <<PubMed>>


Unsupervised machine learning reveals novel traumatic brain injury patient phenotypes with distinct acute injury profiles and long-term outcomes.​

Folweiler KA, Sandsmark DK, Diaz-Arrastia R, Cohen AS, Masino AJ. J Neurotrauma2020 Mar 11. Epub ahead of print. PMID 32008422<<PubMed>>


Common Data Elements: Critical Assessment of Harmonization between Current Multi-Center Traumatic Brain Injury Studies.

Meeuws S, Yue JK, Huijben JA, Nair N, Lingsma HF, Bell MJ, Manley GT, Maas AIR. J Neurotrauma. 2020 Feb 25. doi: 10.1089/neu.2019.6867. [Epub ahead of print]


Invariance of the bifactor structure of mild traumatic brain injury (mTBI) symptoms on the RPQ across time, demographic characteristics, and clinical groups: A TRACK-TBI study.

Agtarap S, Kramer MD, Campbell-Sills L, Yuh E, Mukherjee P, Manley GT, McCrea  MA, Dikmen S, Giacino JT, Stein MB, Nelson LD, and the TRACK-TBI Investigators. (in press). Assessment, 28, 1656-1670. (Published online April, 2020) <<PubMed>>


Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective multicentre study

Yue JK, Yuh EL, Korley FK, Winkler EA, Sun X, Puffer RC, Hansen D, Choy Wm, Taylor SR, Ferguson AR, Huie R, Rabinowitz M, Puccio AM, Mukherjee PM, Vassar MJ, Wang KKW, Diaz-Arrastia R,  Okonkwo DO, Jain S, Manley GT, and the TRACK-TBI Investigators. The Lancet Neurology. 2019 Oct;18(10):953-961


Recovery After Mild Traumatic Brain Injury in Patients Presenting to US Level I Trauma Centers: A Transforming Research and Clinical Knowledge
in Traumatic Brain Injury (TRACK-TBI) Study

Nelson LD, Temkin NR, Dikmen D, Barber J, Giacino JT, Yuh E, Levin HS, McCrea MA, Stein MB, Mukherjee P, Okonkwo DO, Diaz-Arrastia R, Manley GT; and the TRACK-TBI Investigators. JAMA Neurol. 2019 June 3. Epub ahead of print. PMID 31157856. <<PubMed>>


Diagnosing the GOSE: Structural & psychometric properties using item response theory, A TRACK-TBI Pilot Study.

Ranson J, Magnus BE, Temkin N, Dikmen S, Giacino J, Okonkwo DO, Valadka A, Manley GT, Nelson LD; TRACK-TBI Investigators. J Neurotrauma. 2019 Mar 23. Epub ahead of print. PMID 30907261. <<PubMed>>


Preinjury comorbidities are associated with functional impairment and postconcussive symptoms at 3- and 6-months after mild traumatic brain injury: A TRACK-TBI study.

Yue JK*, Cnossen MC*, Winkler EA, Deng H, Phelps RRL, Coss NA, Sharma S, Robinson CK, Suen CG, Vassar MJ, Schnyer DM, Puccio AM, Gardner RC, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Lingsma HF, Manley GT; TRACK-TBI Investigators. Front Neurol. 2019 Mar 20. Epub ahead of print. <<PubMed>>


Functional status examination versus Glasgow Outcome Scale Extended as outcome measures in traumatic brain injuries: How do they compare?

Dikmen S, Machamer J, Manley GT, Yuh EL, Nelson LD, Temkin NR; TRACK-TBI Investigators. J Neurotrauma. 2019 Mar 2. Epub ahead of print. PMID 30827167. <<PubMed>>


Risk of posttraumatic stress disorder and major depression in civilian patients after mild traumatic brain injury: A TRACK-TBI study.

Stein MB, Jain S, Giacino JT, Levin HS, Dikmen SS, Nelson LD, Vassar MJ, Okonkwo DO, Diaz-Arrastia R, Robertson CS, Mukherjee P, McCrea M, Mac Donald CL, Yue JK, Yuh EL, Sun X, Campbell-Sills L, Temkin NR, Manley GT; TRACK-TBI Investigators. JAMA Psychiatry. 2019 Jan 30. Epub ahead of print. PMID 30698636. <<PubMed>>


The functional status examination in mild traumatic brain injury: A TRACK-TBI Sub-Study.​

Zahniser E, Temkin NR, Machamer J, Barber J, Manley GT, Markowitz AJ, Dikmen SS; TRACK-TBI Investigators. Arch Clin Neuropsychol. 2019 Jan 4. Epub ahead of print. PMID 30608522. <<PubMed>>


The Temporal Relationship of Mental Health Problems and Functional Limitations following mTBI: A TRACK-TBI and TED Study

Zahniser E, Nelson LD, Dikmen S, Machamer J, Stein M, Yuh E, Manley GT, Temkin N, and the TRACK-TBI Investigators. J Neurotrauma. 2019 Jan 31. [Epub ahead of print] PMID: 30543138 <<PubMed>>


A comparison of satisfaction with life and the Glasgow Outcome Scale-Extended after traumatic brain injury: An analysis of the TRACK-TBI Pilot study.

Kreitzer NP, Hart KW, Lindsell CJ, Manley GT, Dikmen SS, Ratcliff JJ, Yue JK, Adeoye OM. J Head Tr Rehabil. 2018 Nov 28. PMID 30499935. <<PubMed>>


Sleep, Sleep Disorders, and Circadian Health following Mild Traumatic Brain Injury in Adults: Review and Research Agenda.​ 

Wickwire EM, Schnyer DM, Germain A, Williams SG, Lettieri CJ, McKeon AB, Scharf SM, Stocker R, Albrecht J, Badjatia N, Markowitz AJ, Manley GT. J Neurotrauma. 2018 Aug 24. PMID 29877132. <<PubMed>>


Temporal lobe contusions on computed tomography are associated with impaired 6-month functional recovery after mild traumatic brain injury: A TRACK-TBI study.​

Yue JK, Winkler EA, Puffer RC, Deng H, Phelps RRL, Wagle S, Morrissey MR, Rivera EJ, Runyon SJ, Vassar MJ, Taylor SR, Cnossen MC, Lingsma HF, Yuh EL, Mukherjee P, Schnyer DM, Puccio AM, Valadka AB, Okonkwo DO, Manley GT; TRACK-TBI Investigators. Neurol Res. 2018 Sep 3:1-10. PMID 30175944. <<PubMed>>


Testing a multivariate proteomic panel for TBI biomarker discovery: A TRACK-TBI Pilot study.

Huie JR, Diaz-Arrastia R, Yue JK, Sorani MD, Puccio AM, Okonkwo DO, Manley GT, Ferguson AR; TRACK-TBI Investigators. J Neurotrauma. 2018 Aug 7. PMID 30040754. <<PubMed>>


Rehabilitation trajectories and outcomes in individuals with mild traumatic brain injury and psychiatric histories: A TRACK-TBI Pilot study.

Bertisch H, Satris G, Temkin N, Barber J, Manley GT; TRACK-TBI Investigators. J Head Trauma Rehabil. 2018 Aug 2. Epub ahead of print. PMID 29863617. <<PubMed>>


A Cross-Study Analysis for Reproducible Sub-classification of Traumatic Brain Injury.

Si B, Dumkrieger G, Wu T, Zafonte R, Dodick DW, Schwedt TJ, Li J. Front Neurol. 2018 Aug 13;9:606. <<PubMed>>


Pre-injury employment status as a risk factor for symptomatology and disability in mild traumatic brain injury.

Yue JK, Rick JW, Morrissey MR, Taylor SR, Deng H, Suen CG, Vassar MJ, Cnossen MC, Lingsma HF, Yuh EL, Mukherjee P, Gardner RC, Valadka AB, Okonkwo DO, Cage TA, Manley GT; TRACK-TBI Investigators. NeuroRehabilitation. 2018;43(2):169-182. PMID 30040754. <<PubMed>>


Sub-classifying patients with mild traumatic brain injury: A clustering approach based on baseline clinical characteristics and 90-day and 180-day outcomes.

Si B, Dumkrieger G, Wu T, Zafonte R, Valadka A, Okonkwo DO, Manley GT, Wang L, Dodick DW, Schwedt TJ, Li J. PLoS One. 2018 Jul 11;13(7):e0198741. <<PubMed>>


Concordance of common data elements for assessment of subjective cognitive complaints after mild-traumatic brain injury: a TRACK-TBI Pilot Study

Ngwenya LB, Gardner RC, Yue JK, Burke JF, Ferguson AR, Huang MC, Winkler EA, Pirracchio R, Satris GG, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Manley GT. Brain Inj. 2018 Jun 4:1-8. [Epub ahead of print] <<PubMed>>


Assessment of Follow-up Care After Emergency Department Presentation for Mild Traumatic Brain Injury and Concussion Results From the TRACK-TBI Study

Seabury S, Gaudette E, Goldman D, Markowitz A, Brooks J, McCrea M, Okonkwo D, Manley G, and the TRACK-TBI Investigators. JAMA Network Open2018 May 5.  <<LINK>>


Age-related differences in diagnostic accuracy of plasma GFAP and Tau for identifying acute intracranial trauma on CT: A TRACK-TBI study.

Gardner RC*, Rubenstein R*, Wang KKW, Korley FK, Yue JK, Yuh EL, Mukherjee P, Valadka AB, Okonkwo DO, Diaz-Arrastia R, Manley GT; TRACK-TBI Investigators. J Neurotrauma2018 May 2. PMID 29717620. <<PubMed>>


Performance evaluation of a multiplex assay for simultaneous detection of four clinically relevant TBI biomarkers.

Korley FK*, Yue JK*, Wilson D, Hrusovsky K, Diaz-Arrasta R, Ferguson AR, Yuh EL, Mukherjee P, Wang KKW, Valadka A, Puccio A, Okonkwo DO, Manley GT. J Neurotrauma2018 Apr 25. PMID 29690824. <<PubMed>>


Traumatic brain injury-related symptoms reported by parents: clinical, imaging, and host predictors in children with impairments in consciousness <24 hours.

Evans EA, Asuzu D, Cook N, Caruso P, Townsend E, Costine-Bartell B, Fortes-Monteiro C, Hotz G, Duhaime AC.​ J Neurotrauma. 2018 Apr 21. PMID 29681226. <<PubMed>>


Medical device connectivity challenges outline the technical requirements and standards for promoting big data research and personalized medicine in neurocritical care.

Rodriguez A, Smielewski P, Rosenthal E, Moberg D. Mil Med. 2018 Mar 1;183(suppl_1):99-104. PMID 29635618. <<PubMed>>


Optimizing outcome assessment in multicenter TBI trials: Perspectives from TRACK-TBI and the TBI Endpoints Development Initiative.

Bodien YG, McCrea M, Dikmen S, Temkin N, Boase K, Machamer J, Taylor SR, Sherer M, Levin H, Kramer JH, Corrigan JD, McAllister TW, Whyte J, Manley GT, Giacino JT; TRACK-TBI Investigators. J Head Trauma Rehabil. 2018 Jan 30. Epub ahead of print. PMID 29385010. <<PubMed>>


Functional status examination in patients with moderate-to-severe traumatic brain injuries.​

Machamer J, Temkin NR, Manley GT, Dikmen S. J Neurotrauma. 2018 Mar 13. Epub ahead of print. PMID 29415608. <<PubMed>>


Geriatric traumatic brain injury: Epidemiology, outcomes, knowledge gaps, and future directions

Gardner R, Dams-O-Connor K, Morrissey MR, Manley GT. J NeurotraumaEpub ahead of print. Feb 15, 2018. PMID 29212411. <<PubMed>>


An update on diagnostic and prognostic biomarkers for traumatic brain injury.

Wang KK, Yang Z, Zhu T, Shi Y, Rubenstein R, Tyndall JA, Manley GT. Expert Rev Mol Diagn. 2018 Feb;18(2):165-180. PMID 29338452. <<PubMed>>


Temporal profile of care following mild traumatic brain injury: Predictors of hospital admission, follow-up referral and six-month outcome.​

Yue JK*, Winkler EA*, Sharma S, Vassar MJ, Ratcliff JJ, Korley FK, Seabury SA, Ferguson AR, Lingsma HF, Deng H, Meeuws S, Adeoye OM, Rick JW, Robinson CK, Duarte SM, Yuh EL, Mukherjee P, Dikmen SS, McAllister TW, Diaz-Arrastia R, Gordon WA, Valadka AB, Okonkwo DO, Manley GT; TRACK-TBI Investigators. Brain Inj. 2017;31(13-14):1820-1829. PMID 29166203. <<PubMed>>


Apolipoprotein E epsilon 4 (APOE-ε4) genotype is associated with decreased six-month verbal memory performance after mild traumatic brain injury.​

Yue JK, Robinson CK, Burke JF, Winkler EA, Deng H, Cnossen MC, Lingsma HF, Ferguson AR, McAllister TW, Rosand J, Burchard EG, Sorani MD, Sharma S, Nielson JL, Satris GG, Talbott JF, Tarapore PE, Korley FK, Wang KKW, Yuh EL, Mukherjee P, Diaz-Arrastia R, Valadka AB, Okonkwo DO, Manley GT; TRACK-TBI Investigators. Brain Behav. 2017 Aug 9;7(9):e00791. PMID 28948085. <<PubMed>>


Emergency department blood alcohol level associates with injury factors and six-month outcome after uncomplicated mild traumatic brain injury.

Yue JK, Ngwenya LB, Upadhyayula PS, Deng H, Winkler EA, Burke JF, Lee YM, Robinson CK, Ferguson AR, Lingsma HF, Cnossen MC, Pirracchio R, Korley FK, Vassar MJ, Yuh EL, Mukherjee P, Gordon WA, Valadka AB, Okonkwo DO, Manley GT; TRACK-TBI Investigators. J Clin Neurosci. 2017 Nov;45:293-298. PMID 28789959. <<PubMed>>


Comparing plasma phospho tau, total tau and phospho tau-total tau ratio as acute and chronic traumatic brain injury biomarkers.

Rubenstein R, Chang B, Yue JK, Chiu A, Winkler EA, Puccio AM, Diaz-Arrastia R, Yuh EL, Mukherjee P, Valadka AB, Gordon WA, Okonkwo DO, Davies P, Agarwal S, Fan L, Sarkis G, Yadikar H, Yang Z, Manley GT, Wang KKW; TRACK-TBI Investigators. JAMA Neurol. 2017;74(9):1063-1073. PMID 28738126. <<PubMed>>


Validating multidimensional outcome assessment using the TBI Common Data Elements: An analysis of the TRACK-TBI Pilot sample.​

Nelson LD, Ranson J, Ferguson AR, Giacino JT, Okonkwo DO, Valadka AB, Manley GT, McCrea MA; TRACK-TBI Investigators. J Neurotrauma. 2017 Jun 8. Epub ahead of print. PMID 28595478. <<PubMed>>


The Traumatic Brain Injury Endpoints Development (TED) Initiative: Progress on a public-private regulatory collaboration to accelerate diagnosis and treatment of traumatic brain injury.​

Manley GT, MacDonald CL, Markowitz AJ, Stephenson D, Robbins A, Gardner RC, Winkler EA, Bodien YG, Taylor SR, Yue JK, Kannan L, Kumar A, McCrea MA, Wang KKW; TED Investigators. J Neurotrauma. 2017 Mar 31. Epub ahead of print. PMID 28363253. <<PubMed>>


Development of a prediction model for post-concussive symptoms following mild traumatic brain injury: A TRACK-TBI Pilot study.

Cnossen MC*, Winkler EA*, Yue JK, Okonkwo DO, Valadka AB, Steyerberg EW, Lingsma HF, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2017 Aug 18;34(16):2396-2409. PMID 28343409. <<PubMed>>


Resting state functional connectivity alterations associated with six-month outcomes in mild traumatic brain injury.

Palacios EM, Yuh EL, Chang YS, Yue JK, Schnyer DM, Okonkwo DO, Valadka AB, Gordon WA, Maas AI, Vassar MJ, Manley GT, Mukherjee P. J Neurotrauma. 2017 Apr 15;34(8):1546-1557. PMID 28085565. <<PubMed>>


Toward precision and reproducibility of diffusion tensor imaging: A multicenter diffusion phantom and traveling volunteer study.​

Palacios EM, Martin AJ, Boss MA, Ezekiel F, Chang YS, Yuh EL, Vassar MJ, Schnyer DM, MacDonald CL, Crawford KL, Irimia A, Toga AW, Mukherjee P; TRACK-TBI Investigators. AJNR Am J Neuroradiol. 2017 Mar;38(3):537-545. PMID 28007768. <<PubMed>>


Mild traumatic brain injury: Longitudinal study of cognition, functional status, and post-traumatic symptoms.

Dikmen S, Machamer J, Temkin N. J Neurotrauma. 2017 Apr 15;34(8):1524-1530. PMID 27785968. <<PubMed>>


DRD2 C957T polymorphism is associated with improved 6-month verbal learning following traumatic brain injury.

Yue JK*, Winkler EA*, Rick JW, Burke JF, McAllister TW, Oh SS, Burchard EG, Hu D, Rosand J, Temkin NR, Korley FK, Sorani MD, Ferguson AR, Lingsma HF, Sharma S, Robinson CK, Yuh EL, Tarapore PE, Wang KKW, Puccio AM, Mukherjee P, Diaz-Arrastia R, Gordon WA, Valadka AB, Okonkwo DO, Manley GT; TRACK-TBI Investigators. Neurogenetics. 2017 Jan;18(1):29-38. PMID 27826691. <<PubMed>>


COMT Val158Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury.​

Winkler EA*, Yue JK*, Ferguson AR, Temkin NR, Stein MB, Barber J, Yuh EL, Sharma S, Satris GG, McAllister TW, Rosand J, Sorani MD, Lingsma HF, Vassar MJ, Tarapore PE, Burchard EG, Hu D, Eng C, Puccio AM, Wang KKW, Mukherjee P, Okonkwo DO, Diaz-Arrastia R, Manley GT; TRACK-TBI Investigators. J Clin Neurosci. 2017 Jan;35:109-116. PMID 27769642. <<PubMed>>


Collaborative targeted maximum likelihood estimation for variable importance measure: Illustration for functional outcome prediction in mild traumatic brain injuries.

Pirracchio R, Yue JK, Manley GT, van der Laan MJ, Hubbard AE; TRACK-TBI Investigators. Stat Methods Med Res. 2016 Jun 29. Epub ahead of print. PMID 27363429. <<PubMed>>


Screening for post-traumatic stress disorder in a civilian emergency department population with traumatic brain injury.

Haarbauer-Krupa J, Taylor CA, Yue JK, Winkler EA, Pirracchio R, Cooper SR, Burke JF, Stein MB, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2017 Jan 1;34(1):50-58. PMID 26936513. <<PubMed>>


Plasma anti-glial fibrillary acidic protein autoantibody levels during the acute and chronic phases of traumatic brain injury - A transforming research and clinical knowledge in traumatic brain injury pilot study.

Wang KK*, Yang Z*, Yue JK*, Zhang Z, Winkler EA, Puccio AM, Diaz-Arrastia R, Lingsma HF, Yuh EL, Mukherjee P, Valadka AB, Gordon WA, Okonkwo DO, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2016 Jul 1;33(13):1270-7. PMID 26560343. <<PubMed>>


COMT val (158) met polymorphism is associated with nonverbal cognition following mild traumatic brain injury.

Winkler EA*, Yue JK*, McAllister TW, Temkin NR, Oh SS, Burchard EG, Hu D, Ferguson AR, Lingsma HF, Burke JF, Sorani MD, Rosand J, Yuh EL, Barber J, Tarapore PE, Gardner RC, Sharma S, Satris GG, Eng C, Puccio AM, Wang KK, Mukherjee P, Valadka AB, Okonkwo DO, Diaz-Arrastia R, Manley GT; TRACK-TBI Investigators. Neurogenetics. 2016 Jan;17(1):31-41. PMID 26576546. <<PubMed>>


Circulating brain-derived neurotrophic factor has diagnostic and prognostic value in traumatic brain injury.

Korley FK, Diaz-Arrastia R, Wu AH, Yue JK, Manley GT, Sair HI, Van Eyk J, Everett AD; TRACK-TBI Investigators. J Neurotrauma. 2016 Jan 15;33(2):215-25. PMID 26159676. <<PubMed>>


Association of a common genetic variant within ANKK1 with six-month cognitive performance after traumatic brain injury.

Yue JK*, Pronger AM*, Ferguson AR, Temkin NR, Sharma S, Rosand J, Sorani MD, McAllister TW, Barber J, Winkler EA, Burchard EG, Hu D, Lingsma HF, Cooper SR, Puccio AM, Okonkwo DO, Diaz-Arrastia R, Manley GT; COBRIT Investigators; TRACK-TBI Investigators. Neurogenetics. 2015 Jul;16(3):169-80. PMID 25633559. <<PubMed>>


Genetic data sharing and privacy.​

Sorani MD, Yue JK, Sharma S, Manley GT, Ferguson AR; TRACK-TBI Investigators. Neuroinformatics. 2015 Jan;13(1):1-6. PMID 25326433. <<PubMed>>


Measurement of the glial fibrillary acidic protein and its breakdown products GFAP-BDP biomarker for the detection of traumatic brain injury compared to computed tomography and magnetic resonance imaging.

McMahon PJ, Panczykowski DM, Yue JK, Puccio AM, Inoue T, Sorani MD, Lingsma HF, Maas AI, Valadka AB, Yuh EL, Mukherjee P, Manley GT, Okonkwo DO; TRACK-TBI Investigators. J Neurotrauma. 2015 Apr;32(8):527-33. PMID 25264814. <<PubMed>>


Outcome prediction after mild and complicated mild traumatic brain injury: External validation of existing models and identification of new predictors using the TRACK-TBI Pilot study.

Lingsma HF, Yue JK, Maas AI, Steyerberg EW, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2015 Jan;32(2):83-94. PMID 25025611. <<PubMed>>


ED disposition of the Glasgow Coma Scale 13 to 15 traumatic brain injury patient: Analysis of the Transforming Research and Clinical Knowledge in TBI Study.

Ratcliff JJ, Adeoye O, Lindsell CJ, Hart KW, Pancioli A, McMullan JT, Yue JK, Nishijima DK, Gordon WA, Valadka AB, Okonkwo DO, Lingsma HF, Maas AI, Manley GT; TRACK-TBI investigators. Am J Emerg Med. 2014 Aug;32(8):844-50. PMID 24857248. <<PubMed>>


Diffusion tensor imaging for outcome prediction in mild traumatic brain injury: A TRACK-TBI study.

Yuh EL, Cooper SR, Mukherjee P, Yue JK, Lingsma HF, Gordon WA, Valadka AB, Okonkwo DO, Schnyer DM, Vassar MJ, Maas AI, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2014 Sep;31(17):1457-77. PMID 24742275. <<PubMed>>


Symptomatology and functional outcome in mild traumatic brain injury: Results from the prospective TRACK-TBI study.

McMahon P, Hricik A, Yue JK, Puccio AM, Inoue T, Lingsma HF, Beers SR, Gordon WA, Valadka AB, Manley GT, Okonkwo DO; TRACK-TBI Investigators. J Neurotrauma. 2014 Jan 1;31(1):26-33. PMID 23952719.<<PubMed>>


Acute biomarkers of traumatic brain injury: Relationship between plasma levels of ubiquitin C-terminal hydrolase-L1 and glial fibrillary acidic protein.

Diaz-Arrastia R, Wang KK, Papa L, Sorani MD, Yue JK, Puccio AM, McMahon PJ, Inoue T, Yuh EL, Lingsma HF, Maas AI, Valadka AB, Okonkwo DO, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2014 Jan;31(1):19-25. PMID 23865516. <<PubMed>>


The impact of previous traumatic brain injury on health and functioning: A TRACK-TBI study.

Dams-O'Connor K, Spielman L, Singh A, Gordon WA, Lingsma HF, Maas AI, Manley GT, Mukherjee P, Okonkwo DO, Puccio AM, Schnyer DM, Valadka AB, Yue JK, Yuh EL; TRACK-TBI Investigators. J Neurotrauma. 2013 Dec;30(24):2014-20. PMID 23924069. <<PubMed>>


Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot: Multicenter implementation of the common data elements for traumatic brain injury.

Yue JK, Vassar MJ, Lingsma HF, Cooper SR, Okonkwo DO, Valadka AB, Gordon WA, Maas AI, Mukherjee P, Yuh EL, Puccio AM, Schnyer DM, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2013 Nov;30(22):1831-44. PMID 23815563. <<PubMed>>


Progress in developing common data elements for traumatic brain injury research: Version two--the end of the beginning.

Hicks R, Giacino J, Harrison-Felix C, Manley G, Valadka A, Wilde EA. J Neurotrauma. 2013 Nov 15;30(22):1852-61. PMID 23725058. <<PubMed>>


GFAP-BDP as an acute diagnostic marker in traumatic brain injury: Results from the prospective Transforming Research and Clinical Knowledge in Traumatic Brain Injury study.

Okonkwo DO, Yue JK, Puccio AM, Panczykowski DM, Inoue T, McMahon PJ, Sorani MD, Yuh EL, Lingsma HF, Maas AI, Valadka AB, Manley GT; TRACK-TBI Investigators. J Neurotrauma. 2013 Sep;30(17):1490-7. PMID 23489259. <<PubMed>>


Traumatic brain injury: An international knowledge-based approach.

Manley GT, Maas AI. JAMA. 2013 Aug 7;310(5):473-4. PMID 23925611. <<PubMed>>


Magnetic resonance imaging improves 3-month outcome prediction in mild traumatic brain injury.

Yuh EL, Mukherjee P, Lingsma HF, Yue JK, Ferguson AR, Gordon WA, Valadka AB, Schnyer DM, Okonkwo DO, Maas AI, Manley GT; TRACK-TBI Investigators. Ann Neurol. 2013 Feb;73(2):224-35. PMID 23224915. <<PubMed>>


Recommendations for the use of common outcome measures in traumatic brain injury research.

Wilde EA, Whiteneck GG, Bogner J, Bushnik T, Cifu DX, Dikmen S, French L, Giacino JT, Hart T, Malec JF, Millis SR, Novack TA, Sherer M, Tulsky DS, Vanderploeg RD, von Steinbuechel N. Arch Phys Med Rehabil. 2010 Nov;91(11):1650-1660.e17. PMID 21044708. <<PubMed>>


Common data elements in radiologic imaging of traumatic brain injury.

Duhaime AC, Gean AD, Haacke EM, Hicks R, Wintermark M, Mukherjee P, Brody D, Latour L, Riedy G; Common Data Elements Neuroimaging Working Group Members, Pediatric Working Group Members. Arch Phys Med Rehabil. 2010 Nov;91(11):1661-6. PMID 21044709. <<PubMed>>


Common data elements for research on traumatic brain injury and psychological health: Current status and future development.

Whyte J, Vasterling J, Manley GT. Arch Phys Med Rehabil. 2010 Nov;91(11):1692-6. PMID 21044713. <<PubMed>>


Classification of Traumatic Brain Injury for Targeted Therapies

Saatman K, Duhaime AC, Bullock R, Maas A, Valadka A, Manley GT. Journal of Neurotrauma. 25:719–738 (July 2008). <<PubMed>>